Upneeq is a prescription medication containing oxymetazoline ophthalmic, used to treat blepharoptosis (droopy eyelid) in adults and children aged 13 and older. It may also be used for other purposes not listed in this guide.

Consult your doctor or pharmacist before using Upneeq with other medications, especially: 

• Heart or blood pressure medications 
• Beta blockers (e.g., atenolol, carvedilol) 
• MAO inhibitors (e.g., isocarboxazid, phenelzine) This list is not exhaustive. Inform your healthcare provider about all medications, including over-the-counter drugs, vitamins, and herbal products. 

1. Preparation: 

• Wash your hands before applying the medication. 
• Shake the eye drops well before each use. 

2. Application: 

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. 
• Hold the dropper above your eye and squeeze one drop into the pocket. 
• Close your eyes for 1-2 minutes. 
• Use only the recommended number of drops. 

3. Contact Lenses: 

• Do not use Upneeq while wearing soft contact lenses. Wait at least 15 minutes before inserting lenses after applying the medication. 

4. Safety Precautions: 

• Do not touch the tip of the dropper or place it directly on your eye to avoid contamination. 
• Store the medicine upright at room temperature. Do not freeze. 
• Keep out of reach of children. Dispose of each single-use container after one use, even if there is still medicine left. 

If You Miss a Dose: 

• If using Upneeq as needed, skip any missed dose if it’s almost time for your next dose. Do not double up on doses. 

If You Overdose: 

• An overdose is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if accidentally swallowed. 

What to Avoid: 

• Do not use other eye medications unless directed by your doctor. 

Possible Side Effects: 

Emergency Side Effects: Seek immediate medical help if you experience: 

• Signs of an allergic reaction (hives, difficulty breathing, swelling of face, lips, tongue, or throat). 
• Light-headedness or feeling like you might pass out. 
• Ongoing or worsening eye redness. 
• Eye pain or changes in vision. 

Common Side Effects: May include: 

• Mild burning or stinging of the eye 
• Blurred vision, watery eyes 
• Mild headache, dizziness, nervousness 

Note: This is not a complete list of side effects. Contact your doctor for medical advice and report side effects to the FDA at 1-800-FDA-1088.

Before Using Upneeq: 

Do not use Upneeq if you have: 

• Allergies to its ingredients 
• High or low blood pressure 
• Heart problems 
• Sjögren’s syndrome 
• Blood circulation issues 
• Glaucoma 
• Eye injury or infection 

Warnings: 

• Follow all directions on the label and package. 
• Inform all healthcare providers about your medical conditions, allergies, and medications. 
• Pregnancy and Breastfeeding: 
  • Always follow the directions on the medicine label for use in children. Do not administer to children under 6 years old without medical advice. 

By signing the consent form, you acknowledge: 

• You do not have any of the contraindicated conditions listed. 
• You do not take any of the medications that are contraindicated. 
• You understand how to use Upneeq and when to stop using it. 
• You willingly release Jenifer Gibson Staff Services LLC, DBA Skin and Tonic, and GVGJRDOPLLC from any responsibility or harm resulting from the use of Upneeq. 

By signing the consent form, you acknowledge: 

• You do not have any of the contraindicated conditions listed. 
• You do not take any of the medications that are contraindicated. 
• You understand how to use Upneeq and when to stop using it. 
• You willingly release Jenifer Gibson Staff Services LLC, DBA Skin and Tonic, and GVGJRDOPLLC from any responsibility or harm resulting from the use of Upneeq. For any questions or concerns, please contact our staff at 810-522-4799.